The New Corona is More Dangerous than Flu or Ebola

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Often, the new coronavirus that is rampant in China is unknown. One thing is certain, however, is that infection with the virus causes catastrophic events throughout the body. (Reference article: “The new corona is more dangerous than flu or Ebola”)

Past coronaviruses transmitted from animals to humans, such as SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome), unlike normal cold viruses, spread to many organs and cause various symptoms Was. The new virus is no exception. (Reference article: “MERS vaccine, the reason why development does not proceed”)

That’s why it killed more than 2,000 people in just over a month. The mortality rate seems to be about one-fifth of SARS, but the number of deaths is already higher than SARS, and the spread of infection is fast. The World Health Organization (WHO) has named the new coronavirus disease COVID-19.

What happens to the body when infected with the coronavirus? The new type of gene is so similar to SARS that it was named SARS-CoV-2 after SARS. Combining the early research results of the new epidemic with the knowledge learned from past SARS and MERS, the answer is likely to come to light. (Reference article: “What’s going on with the new type of pneumonia and blocked Wuhan?”)

Begins in the lungs and ends in the lungs.

COVID-19 is the same respiratory disease as influenza, which can be said to begin and end in the lungs.

Usually, the infection spreads when the infected person coughs or sneezes and splashes droplets. Specific symptoms, similar to the flu, may start with fever and cough, eventually develop pneumonia and progress to more severe symptoms.

After the SARS epidemic, WHO announced that coronavirus-induced pneumonia generally became more severe in three phases. Virus replication, immune overreaction, and lung collapse.

Of course, not all patients will experience these three stages. Only 25% of SARS patients progressed to respiratory failure. On the other hand, according to the initial data of COVID-19, about 82% of infected people seem to be mild.

Drilling further, the new coronavirus appears to follow a pattern similar to SARS in other ways, said Matthew B. Freeman, an associate professor at the University of Maryland Medical School, who studies highly pathogenic coronaviruses.

Currently, testing and confirmation of infection with COVID-19 is carried out in a variety of ways, but in a study published on emerging germs and infections, Chinese scientists found evidence of rapid detection with saliva and feces. Have been reported for COVID-19 viruses. These reports were performed with the help of oral, rectal, and blood samples.

The study was performed at Wuhan China Hospital, with a sample of 178 patients. The authors of this study observed viral nucleotides in anal or blood samples, even when saliva did not contain diagnostic markers. The results also showed that the timing of the sample changes was also important. For example, on day 1 of the disease, 80% of the oral samples were positive in a small group of patients, by day 5, 75% of the anal samples were positive for COVID-19 viral RNA, and during the same time period, only 50% of the samples were The mouth correctly indicated that the virus was positive. If you are confused with this information, the simplest and most concise result is that the patient’s oral sample performs more accurately in the early stages, and the anal and blood samples in the more acute stages of the disease.

The results of this study for the first time show that COVID-19 can be transmitted through the respiratory, fecal, oral or body fluids. They also warn that a patient with a negative test sample after a few days of illness may still be able to transmit the virus.

Corona attacks the body of patients with the help of several contingency maps / Different diagnostic methods work more strongly in each disease period

In a report from the Chinese Centers for Disease Control, the authors describe how to isolate the virus from the stool sample of a patient with COVID-19. Although oral secretions, sneezes and coughs appear to be one of the most important modes of 2019-nCoV transmission, these are not the only means of transmission. The finding shows that the stool can contaminate the hands and quickly contaminate food and water if the hands are not properly washed.

At BMJ, Chinese scientists today examined the clinical findings of 62 COVID-19 patients from seven hospitals in Zhejiang Province, China. None of the patients died and only one patient was admitted to the intensive care unit. Of the 62 patients, 48 ​​(77%) had fever, 50 (81%) cough, 32 (52%) pain and Muscle fatigue and 21 (34%) patients had headaches. The authors said that only two patients (3%) had shortness of breath at the time of admission.

The authors said that compared to patients in Wuhan, patients seen in Zhejiang had relatively mild symptoms. None of the patients were exposed to the Wuhan seafood market related to the virus origin, and all were in contact with another infected person. Patients who had experienced symptoms for more than 10 days were likely to have underlying problems.

The authors also provide a timeline for infection: “Of the 56 patients who could provide a precise date of close contact with a person with confirmed or suspected SARS-CoV-2 infection, the median time to infection was The direct onset was about 4 days (range between 5–3 days) and the median time to symptom onset to hospitalization was 2.0 (1.0–4.3) days.

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Summary

Often, the new coronavirus that is rampant in China is unknown. One thing is certain, however, is that infection with the virus causes catastrophic events throughout the body. (Reference article: The new corona is more dangerous than flu or Ebola

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