Detection of New Coronavirus in 40 Minutes from Yone University

Research teams at the University of California, San Francisco and others have developed a technology to detect the new coronavirus extracted from the nose and throat wipes in about 40 minutes, and published it in the American science magazine “Nature Biotechnology”. Apply genome editing technology that can freely manipulate genetic information. It takes 30 to 40 minutes to complete the conventional PCR test, which takes about 2 hours.

The research team applied genome editing technology and combined it with existing methods for amplifying DNA from RNA of viruses. The accuracy was confirmed with samples from 36 new coronavirus-infected individuals and 42 patients with other viral respiratory infections.

Compared to the “RT-PCR method” used by the US Centers for Disease Control, the results were 95% positive and 100% negative. Since no special equipment is required, it may be a method that is easy to spread.

Researchers at the University of Berkeley apply similar technology to the genome editing technology “Crisper Cass 9” developed in 2012. It uses a guide RNA that recognizes part of the virus sequence, an enzyme that acts as a scissor, and a DNA fragment for detection. When the target region is found, the scissors cleave the DNA and this change can be used as a clue.

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