Scientists have Already Used PSC for Bioengineering Stomach

Scientists working on the bioengineering of the entire human gastrointestinal system in the laboratory reported. 

This is the first time that scientists have been able to fully grow human esophagus tissue from pluripotent stem cells (PSC), which can form any type of tissue in the body, writes ScienceDaily.

The study is the latest achievement of researchers from the Cincinnati Children’s Center for Stem Cells and Organic Medicine, USA. The Center is developing new ways of studying congenital defects and diseases that affect millions of people with gastrointestinal disorders, such as stomach reflux, cancer, etc. Center scientists have already used PSC for bioengineering of the intestines of the human, stomach, colon and liver.

“Disturbances of the esophagus and trachea are quite common in humans, so the organoids of the human esophagus can be very useful,” said Jim Wells, chief researcher at the Center and lead researcher. “In addition to the new model for the study of birth defects such as esophageal atresia, organelles can be used to study diseases such as eosinophilic esophagitis and Barrett metaplasia, or in bioengineering.”

In this study, specialists who worked in the departments of developmental biology, oncology, allergy and immunology and endocrinology of the Center participated.

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