How did Humans have an Evolutionary Advantage

The Canadian Debate Foundation The Donald Lee Center team found one answer in the human evolutionary gene. The researchers believe that dozens of genes, previously thought to play a similar role among other organisms, could actually explain why humans have a special role in humans.

These genes encode transcription factors (TFs) that regulate gene expression to produce specific proteins.

Transcription factors recognize certain snippets of DNA code called motifs and use them as landing points to bind DNA to turn genes on or off.

Previous studies have suggested that transcription factors that appear similar between different organisms bind to similar motifs in various species, including Drosophila and humans.

But Timothy Hughes, a team at Donnelly Cell and Biomolecular Research Center, said new research has not always done that.

In a paper published in the recent issue of Nature Genetics, the research team applied the new method of calculation to obtain more accurate predictions of the sequences of motifs that each transcription factor binds in many different species I wrote.

This study showed that some sub-grade transcription factors are functionally much more diverse than previously thought.

Differences in species are due to differences in gene regulation

Dr. Sam Lambert, Ph.D. lead author of the paper at Professor Hughes’ s laboratory and currently a postdoctoral fellow at Cambridge University in England, said, “There is a possibility that a number of transcription factors, which are closely related to each other, He said.

He explained that this “is important in the species difference, that it has the potential to have new functions by controlling other genes.”

A picture depicting the motive divergence between human transcription factors and their corresponding other transcription factors. The C2H2 ZF protein shows a variety of functions between closely related species, such as humans and chimpanzees. CREDIT: Sam Lambert

A picture depicting the motive divergence between human transcription factors and their corresponding other transcription factors. The C2H2 ZF protein shows a variety of functions between closely related species, such as humans and chimpanzees.

99% of the genome may have dozens of transcription factors that recognize different motifs between the same species in both humans and chimpanzees, affecting hundreds of different gene expressions.

Reviewer overview

How did Humans have an Avolutionary advantage - /10

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The Canadian Debate Foundation The Donald Lee Center team found one answer in the human evolutionary gene.

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